pharmacological group metabolic agent.
Pharmacological effects are due to the complex effect of the components included in the cytoflavin preparation.
Succinic acid is an endogenous intracellular metabolite of the Krebs cycle, which performs a universal function as an energy synthesizer in the cells of the body.
With the participation of the coenzyme flavin adenine dinucleotide (FAD), succinic acid is rapidly converted by the mitochondrial enzyme succinct dehydrogenase to fumaric acid and then to other metabolites of the tricarboxylic acid cycle. It stimulates aerobic glycolysis and ATP synthesis in cells.
The end product of succinic acid metabolism in the Krebs cycle is carbon dioxide and water. Succinic acid improves tissue respiration by activating electron transport in the mitochondria.
Riboflavin (vitamin B2) is a FAD coenzyme that activates succinct dehydrogenase and other redox reactions of the krebs cycle.
Nicotinamide (vitamin PP) is an arid of nicotinic acid. Nicotinamide in cells, through a cascade of biochemical reactions, is transformed into the form of nicotinamide adenine nucleotide (NAD) and its phosphate (NADP), activating nicotinamide-dependent enzymes of the krebs cycle, which are necessary for the cellular respiration and stimulation of ATP synthesis.
Inosine is a derivative of purine, a precursor to ATP. It has the ability to activate a series of enzymes of the krebs cycle, stimulating the synthesis of key enzymes-nucleotides: FAD and NAD.
Therefore, all components of the cytoflavin preparation are natural metabolites in the body and stimulate tissue respiration.Metabolic correction of energy, antihypoxic and antioxidant activity of the drug, which determine its pharmacological properties and therapeutic efficacy, are due to the complementary action of succinic acid, inosine, nicotinamide and riboflavin.
Indications of the drug Cytoflavin
In adults in complex therapy:
- consequences of cerebral infarction,
- other cerebrovascular diseases (cerebral atherosclerosis, hypertensive encephalopathy),
- neurasthenia (increased irritability, fatigue, loss of capacity for prolonged mental and physical stress).
Method of administration and dosage
Inside, 2 tables. 2 times a day with an interval between doses of 8-10 hours. Tablets should be taken at least 30 minutes before meals, without chewing, washed down with water (100 ml).
It is recommended to take the drug in the morning and in the evening (no later than 18 hours).
The duration of the course of treatment is 25 days. The appointment of a repeated course is possible with an interval of at least 1 month.